Features of Zydena Generic Drug
Zudena is a generic version of Zydena, an ED treatment drug designed to improve symptoms of erectile dysfunction (ED).

This drug contains the same ingredients as Zydena, which was developed as an ED treatment drug for Asians, characterized by yellow triangular tablets.

Effects of Zudena Generic Drug
Udenafil is the main component of generic Zydena, and its mechanism of action involves inhibiting PDE-5 (phosphodiesterase type 5), an enzyme that suppresses erection.

The PDE-5 enzyme breaks down cyclic guanosine monophosphate (cGMP), which is essential for erection.

When cGMP is broken down, erection becomes impossible, a condition known as ED (erectile dysfunction).

Udenafil inhibits the PDE-5 enzyme, which has the effect of dilating blood vessels around the penis and relaxing the muscles of the internal penile tissue, known as the corpus cavernosum.

This effect causes vasodilation and muscle relaxation, thereby allowing more blood to flow into the tissues inside the penis, known as the corpus cavernosum, promoting erection.

How Long Does Zudena's Effect Last?
Its effect is said to last for 11 to 13 hours, but taking this drug does not force an erection; it only occurs when you are sexually stimulated or aroused.

Dosage of Zydena Generic Drug

You can purchase this drug in doses of 100 mg or 200 mg on this website.

If you are taking it for the first time, use a pill cutter or similar tool to split the tablet and start with half a dose.

Other
The Zydena generic drug is an ED treatment that combines the erectile efficacy of Viagra, the rapid action of Levitra, and the long-lasting effect of Cialis.

The original drug Zydena was launched in 2005 and became a popular product, capturing the second-largest market share in the erectile dysfunction treatment market within two years.

Currently, this product is sold in over 30 countries, including Asian nations and Russia.

※The packaging may vary depending on shipping times.

Related Pages for Zydena Generic Drug
List of other erectile dysfunction treatment drugs
・ED Treatment Drugs

Timing of Medication
The correct way to take Zudena is on an empty stomach, approximately 30 minutes to 1 hour before sexual activity.

After the first dose, wait at least 24 hours before taking another dose.

Recommended Dosage
Zudena sold on this website is available in 100mg/200mg, and can be split using a pill cutter for half-dose administration.

Note: Although some may take 2-3 times the prescribed dose at once to pursue stronger effects, this does not significantly enhance the drug's efficacy.

The maximum dose per sexual activity should not exceed 100mg.

Recommended Dosage
For first-time users of medications containing Udenafil (the main ingredient in Zudena), it is recommended to start with 100mg.

Effect of Food
Although Zudena is less affected by food, please note:
• Foods such as fat-containing milk can form a film on the stomach wall that hinders absorption.
• It is recommended to take 30 minutes before meals to maximize Udenafil absorption.
• If taken after meals, wait at least 2 hours.
• High-fat foods such as grilled meat or fried foods may require a longer digestion time.

Normal eating can be resumed after the drug is fully absorbed.

Effect of Alcohol
Although it can be used with alcohol, vasodilatory effects may accelerate intoxication, so avoid excessive alcohol consumption.

Contraindicated Groups
• Patients with cardiovascular disease (those who should not engage in sexual activity)
• Patients with severe hepatic impairment
• Patients with hypotension or uncontrolled hypertension
• Those who have had a stroke or myocardial infarction within the last 6 months

※Please strictly follow your doctor's instructions.

Main Side Effects
The main side effects include decreased blood pressure due to vasodilation, eye congestion, facial flushing, palpitations, nasal congestion, etc.

These are believed to be caused by vasodilation, and the side effects may lessen when increased sexual desire enhances blood flow to the penis.

Specific Symptoms
Specific symptoms include visual abnormalities, such as feeling like wearing blue-tinted glasses or being unable to distinguish between blue and green.

In most cases, this condition is temporary and causes no issues, but if vision deteriorates severely, there is a risk of developing Nonarteritic Anterior Ischemic Optic Neuropathy (NAION).

If you experience sudden vision loss or impairment, consult an ophthalmologist or other specialist.

Additionally, if you have a painful erection lasting more than four hours, you may have priapism.

If your erection persists beyond four hours, seek immediate medical attention.

※ What is Nonarteritic Anterior Ischemic Optic Neuropathy (NAION)?
When blood supply to the optic nerve ceases, optic nerve cells begin to dysfunction or die. This condition is called ischemic optic neuropathy.
While the causal relationship remains unclear, a slight correlation has been reported between this disease and individuals taking erectile dysfunction medications.

※ What is priapism?
Priapism, also known as persistent erection, refers to a condition where the penis remains erect and cannot return to normal or has difficulty returning to normal.
It is also termed penile rigidity.
The primary cause is believed to be a rupture in the arterial system of the penile corpus cavernosum.
If your erection does not subside after four consecutive hours, seek immediate medical care.

Contraindicated Drug Combinations
Drugs that should not be taken together are those incompatible with Zydena generic drugs and cannot be used simultaneously.

・Nitrates and nitric oxide donors
(Nitroglycerin, Amyl Nitrite, Isosorbide Dinitrate)
Concomitant use may enhance the antihypertensive effect.

・Amiodarone Hydrochloride
(Ancaron Tablets)
Concomitant use may enhance the QTc prolongation effect of amiodarone hydrochloride.

・CYP3A4 inhibitors
(Antifungal drugs, anti-HIV drugs, Telithromycin, Nelfinavir, Ketoconazole, Itraconazole, Ritonavir, Saquinavir, Nelfinavir, Atazanavir, etc.)
The plasma concentration of this drug may increase, thereby prolonging its half-life in the blood.

Contraindications for Concomitant Use with Other Drugs
Drugs that require caution when used with Zydena generic may also interact with other drugs.

・Grapefruit (including juice)
The component furanocoumarin inhibits the action of metabolic enzymes in the body, slowing down drug breakdown. As a result, drug components may be absorbed in larger quantities than needed, potentially leading to increased efficacy and side effects.

・Antihypertensive drugs
The generic name Zydena has the effect of lowering blood pressure. Concomitant use with antihypertensive drugs may cause low blood pressure symptoms, such as temporary dizziness or lightheadedness.

Reference Sites
In addition to the product instructions in the country of sale, we also refer to the following websites for information on dosage instructions, side effects, contraindications, and precautions for use with other drugs.
・Udenafil - Wikipedia

• Please store in a place away from direct sunlight, dry and cool.

• Please keep out of reach of children.

• To avoid accidental ingestion or product deterioration, do not change the original packaging container.

• If taking the remaining medicine in a single package over several times, store it as airtight as possible and consume it within 2 days.

• Do not take or use products beyond the indicated expiration date.

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